Challenges for Drug Repurposing in Covid-19

The corona virus disease (COVID-19) contagion has affected an estimated 16 million persons and caused 0.6 million deaths worldwide by September 2020. The contagion has led to a rush to repurpose existing drugs, although the elementary substantiation base is of variable quality. The enriching knowledge of the virology and clinical presentation of COVID-19 is leading to a broadening pool of implicit pharmacological targets. The intention is to describe executive and pharmacological aspects of medicine repurposing and to identify medicines proposed for repurposing in COVID-19 hung on registered clinical trials, bandying the substantiation to support their use in the treatment of this distemper. The challenges of the correct interpretation of breathing pre-clinical/ clinical substantiation as well as the generation of new substantiation concerning medicine repurposing in COVID-19 will also be agitated.

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